TY - JOUR
T1 - Associated Factors for Chronic Kidney Disease in Patients with Diabetes Mellitus 2
T2 - Retrospective Study
AU - Goicochea-Rios, Evelyn Del Socorro
AU - Yupari-Azabache, Irma Luz
AU - Gómez Goicochea, Néstor Iván
AU - Otiniano, Nélida Milly
N1 - Publisher Copyright:
© 2024 Goicochea-Rios et al.
PY - 2024
Y1 - 2024
N2 - Introduction: Chronic kidney disease affects the quality of life of people with diabetes mellitus, increases cardiovascular risk, and has high social costs. Objective: To determine associated factors for chronic kidney disease in people with diabetes mellitus type 2. Material and Methods: Retrospective cohort study with 371 patients evaluated in primary care for diabetes mellitus. Information on age, sex, disease duration, comorbidity and laboratory results was obtained. Patients of both sexes attended between 2022 and 2024 were included. Patients with other renal diseases or referrals were excluded. Logistic regression analysis was performed to identify associated factors. Results: Males (p = 0.014), age >60 years, (p = 0.01) uncontrolled diabetes (HbA1C >7.99%±1.84) and disease duration over 20 years (p = 0.02) are associated factors for chronic kidney disease (CKD). HbA1c had significant differences between those with and those without CKD. The most frequent comorbidities are arterial hypertension (70%), dyslipidemia (43%), overweight/obesity (44%) and anemia (31%). CKD stage G2 is the most frequent (45%). One hundred percent of patients in G1 and G2 CKD stages have an elevated microalbuminuria/creatinuria rate, and 13% of patients between G3a and G4 stages have this rate within normal values. Most patients receive nephroprotection with ARA II and ACEIs. Conclusion: It is important to screen for kidney disease in patients with diabetes mellitus type 2 who are male, over 60 years of age, with uncontrolled HbA1c and prolonged disease duration, as well as to treat comorbidities and nephroprotection regardless of the stage of chronic kidney disease.
AB - Introduction: Chronic kidney disease affects the quality of life of people with diabetes mellitus, increases cardiovascular risk, and has high social costs. Objective: To determine associated factors for chronic kidney disease in people with diabetes mellitus type 2. Material and Methods: Retrospective cohort study with 371 patients evaluated in primary care for diabetes mellitus. Information on age, sex, disease duration, comorbidity and laboratory results was obtained. Patients of both sexes attended between 2022 and 2024 were included. Patients with other renal diseases or referrals were excluded. Logistic regression analysis was performed to identify associated factors. Results: Males (p = 0.014), age >60 years, (p = 0.01) uncontrolled diabetes (HbA1C >7.99%±1.84) and disease duration over 20 years (p = 0.02) are associated factors for chronic kidney disease (CKD). HbA1c had significant differences between those with and those without CKD. The most frequent comorbidities are arterial hypertension (70%), dyslipidemia (43%), overweight/obesity (44%) and anemia (31%). CKD stage G2 is the most frequent (45%). One hundred percent of patients in G1 and G2 CKD stages have an elevated microalbuminuria/creatinuria rate, and 13% of patients between G3a and G4 stages have this rate within normal values. Most patients receive nephroprotection with ARA II and ACEIs. Conclusion: It is important to screen for kidney disease in patients with diabetes mellitus type 2 who are male, over 60 years of age, with uncontrolled HbA1c and prolonged disease duration, as well as to treat comorbidities and nephroprotection regardless of the stage of chronic kidney disease.
KW - chronic kidney disease
KW - diabetes mellitus type 2
KW - stages of kidney disease
UR - http://www.scopus.com/inward/record.url?scp=85211227974&partnerID=8YFLogxK
U2 - 10.2147/IJNRD.S489891
DO - 10.2147/IJNRD.S489891
M3 - Article
AN - SCOPUS:85211227974
SN - 1178-7058
VL - 17
SP - 289
EP - 300
JO - International Journal of Nephrology and Renovascular Disease
JF - International Journal of Nephrology and Renovascular Disease
ER -