Neuropharmacological Validation of Clinopodium pulchellum (Panizara): Unveiling the Anxiolytic and Antidepressant Mechanism via In Vivo Models and Molecular Docking

Juan E. Valdiviezo-Campos; Ramiro Fiestas-Jacinto; Karyn A. Olascuaga-Castillo; Segundo G. Ruiz-Reyes; Susana R. Rubio-Guevara; Roger A. Rengifo-Penadillos; Junior F. Siguas-Peña

doi:10.3390/plants15101511

Neuropharmacological Validation of Clinopodium pulchellum (Panizara): Unveiling the Anxiolytic and Antidepressant Mechanism via In Vivo Models and Molecular Docking

Juan E. Valdiviezo-Campos
, Ramiro Fiestas-Jacinto
, Karyn A. Olascuaga-Castillo
, Segundo G. Ruiz-Reyes
, Susana R. Rubio-Guevara
, Roger A. Rengifo-Penadillos
, Junior F. Siguas-Peña

Research output: Contribution to journal › Article › peer-review

Original language	English
Article number	1511
Journal	Plants
Volume	15
Issue number	10
DOIs	https://doi.org/10.3390/plants15101511
State	Published - 1 May 2026
Externally published	Yes

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10.3390/plants15101511

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Valdiviezo-Campos, J. E., Fiestas-Jacinto, R., Olascuaga-Castillo, K. A., Ruiz-Reyes, S. G., Rubio-Guevara, S. R., Rengifo-Penadillos, R. A., & Siguas-Peña, J. F. (2026). Neuropharmacological Validation of Clinopodium pulchellum (Panizara): Unveiling the Anxiolytic and Antidepressant Mechanism via In Vivo Models and Molecular Docking. Plants, 15(10), Article 1511. https://doi.org/10.3390/plants15101511

@article{afa0614ede2542d6a6fc1ab913197dcc,

title = "Neuropharmacological Validation of Clinopodium pulchellum (Panizara): Unveiling the Anxiolytic and Antidepressant Mechanism via In Vivo Models and Molecular Docking",

keywords = "CUMS-forced swim test, essential oil, molecular docking, neuropharmacological activity, panizara, plus maze test",

author = "Valdiviezo-Campos, \{Juan E.\} and Ramiro Fiestas-Jacinto and Olascuaga-Castillo, \{Karyn A.\} and Ruiz-Reyes, \{Segundo G.\} and Rubio-Guevara, \{Susana R.\} and Rengifo-Penadillos, \{Roger A.\} and Siguas-Pe{\~n}a, \{Junior F.\}",

note = "Publisher Copyright: {\textcopyright} 2026 by the authors.",

year = "2026",

month = may,

day = "1",

doi = "10.3390/plants15101511",

language = "English",

volume = "15",

journal = "Plants",

issn = "2223-7747",

publisher = "Multidisciplinary Digital Publishing Institute (MDPI)",

number = "10",

}

Valdiviezo-Campos, JE, Fiestas-Jacinto, R, Olascuaga-Castillo, KA, Ruiz-Reyes, SG, Rubio-Guevara, SR, Rengifo-Penadillos, RA & Siguas-Peña, JF 2026, 'Neuropharmacological Validation of Clinopodium pulchellum (Panizara): Unveiling the Anxiolytic and Antidepressant Mechanism via In Vivo Models and Molecular Docking', Plants, vol. 15, no. 10, 1511. https://doi.org/10.3390/plants15101511

Neuropharmacological Validation of Clinopodium pulchellum (Panizara): Unveiling the Anxiolytic and Antidepressant Mechanism via In Vivo Models and Molecular Docking. / Valdiviezo-Campos, Juan E.; Fiestas-Jacinto, Ramiro; Olascuaga-Castillo, Karyn A. et al.
In: Plants, Vol. 15, No. 10, 1511, 01.05.2026.

Research output: Contribution to journal › Article › peer-review

TY - JOUR

T1 - Neuropharmacological Validation of Clinopodium pulchellum (Panizara)

T2 - Unveiling the Anxiolytic and Antidepressant Mechanism via In Vivo Models and Molecular Docking

AU - Valdiviezo-Campos, Juan E.

AU - Fiestas-Jacinto, Ramiro

AU - Olascuaga-Castillo, Karyn A.

AU - Ruiz-Reyes, Segundo G.

AU - Rubio-Guevara, Susana R.

AU - Rengifo-Penadillos, Roger A.

AU - Siguas-Peña, Junior F.

PY - 2026/5/1

Y1 - 2026/5/1

KW - CUMS-forced swim test

KW - essential oil

KW - molecular docking

KW - neuropharmacological activity

KW - panizara

KW - plus maze test

UR - https://www.scopus.com/pages/publications/105040106949

U2 - 10.3390/plants15101511

DO - 10.3390/plants15101511

M3 - Article

AN - SCOPUS:105040106949

SN - 2223-7747

VL - 15

JO - Plants

JF - Plants

IS - 10

M1 - 1511

ER -

Neuropharmacological Validation of Clinopodium pulchellum (Panizara): Unveiling the Anxiolytic and Antidepressant Mechanism via In Vivo Models and Molecular Docking

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