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Presentación tomográfica con aspecto miliar en paciente inmunocomprometido con candidiasis pulmonar: reporte de caso

  • Luis Alejandro Rodríguez-Hidalgo
  • , Diana Cecilia Ruiz-Caballero
  • , César Augusto Colunche-Narváez
  • , Amalia Guadalupe Vega-Fernández
  • , Theresina Elizabeth Rodríguez-Sáenz

    Research output: Contribution to journalArticlepeer-review

    Abstract

    INTRODUCTION Candida albicans infection shows a wide range of patterns on chest computed tomography, including ground glass opacities and consolidation, with the miliary pattern being the least frequent. The miliary pattern is not exclusive to tuberculosis. Fungal lung infections are rare and potentially fatal. Colonization by Candida albicans, associated with impaired immunity, requires early empirical antifungal therapy to improve survival. CASE REPORT 48-year-old male patient with persistent productive cough, mucopurulent expectoration, dyspnea on moderate exertion, night sweats, elevated temperature, and weight loss. Chest tomography revealed miliary interstitial lung disease, and he was prescribed antituberculosis treatment. Diagnostic video bronchoscopy showed two tumors in the right main bronchus. Studies of the samples revealed the presence of Candida albicans in the pulmonary parenchyma. A new contrasted chest tomographic study reported a heterogeneous lesion in the esophagus. The pathologic result of the biopsy concluded the presence of moderately differentiated keratinized infiltrating squamous cell carcinoma. The patient died. DISCUSSION The miliary tomographic pattern requires a broader approach for accurate diagnosis. The reported case presented with oral candidiasis and impaired immunity. Previous colonization associated with impaired immunity is the most important factor found for disseminated candidiasis. CONCLUSION The miliary radiological pattern is not exclusive to tuberculosis, warranting a more precise diagnostic approach. It is important to diagnose disseminated candidiasis in order to initiate early antifungal therapy and thus improve survival.

    Translated title of the contributionTomographic presentation with miliary appearance in an immunocompromised patient with pulmonary candidiasis: A case report
    Original languageSpanish
    Article numbere2975
    JournalMedwave
    Volume24
    Issue number11
    DOIs
    StatePublished - 1 Dec 2024

    UN SDGs

    This output contributes to the following UN Sustainable Development Goals (SDGs)

    1. SDG 3 - Good Health and Well-being
      SDG 3 Good Health and Well-being

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