Síntomas gastrointestinales como manifestaciones extrapulmonares en pacientes con COVID-19.Unarevisiónnarrativa

Vivian Sánchez-Toro, Gustavo Adolfo Vásquez-Tirado, Edinson Dante Meregildo-Rodríguez, Niler Manuel Segura-Plasencia, Yessenia Katherin Arbaiza-Avalos, Víctor Serna-Alarcón

Research output: Contribution to journalArticlepeer-review

1 Scopus citations


Background: SARS-CoV-2 infection mainly affects the respiratory system; but, multiple extrapulmonary manifestations have also been observed in various systems and organs. The epithelial cells of the digestive tract and hepatobiliary tree express ECA2 and TMPRSS2 necessary for viral entry, on the other hand, viral RNA has been detected in stool samples, even after having become negative in respiratory samples. The presence of clinical digestive manifestations is associated with a higher viral load and can sometimes be the only manifestations of COVID-19, even in the absence of respiratory symptoms. The most common symptoms are anorexia and diarrhea, nausea, vomiting, and abdominal pain, the latter being characteristic of seriously ill patients. Gastrointestinal bleeding, hemorrhagic colitis, or acute hepatitis are very rare. In a patient with gastrointestinal manifestations, COVID-19 should be considered within the differential diagnosis.

Translated title of the contributionGastrointestinal symptoms as extrapulmonary manifestations in patients with COVID-19. A narrative review
Original languageSpanish
Pages (from-to)398-403
Number of pages6
JournalRevista del Cuerpo Medico Hospital Nacional Almanzor Aguinaga Asenjo
Issue number3
StatePublished - Nov 2021


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