Symmetry-Aware Machine Learning for the Diagnosis of Alzheimer’s Disease and Detection of Mild Cognitive Impairment Using Biomarkers

Orlando Iparraguirre-Villanueva; José Luis Herrera Salazar; Gloria Castro-Leon; Hernán Ochoa-Carbajal; Henry Chero-Valdivieso; Rosalynn Ornella Flores-Castañeda

doi:10.3991/ijoe.v22i01.58189

Symmetry-Aware Machine Learning for the Diagnosis of Alzheimer’s Disease and Detection of Mild Cognitive Impairment Using Biomarkers

Orlando Iparraguirre-Villanueva
, José Luis Herrera Salazar
, Gloria Castro-Leon
, Hernán Ochoa-Carbajal
, Henry Chero-Valdivieso
, Rosalynn Ornella Flores-Castañeda

Research output: Contribution to journal › Article › peer-review

Original language	English
Pages (from-to)	21-39
Number of pages	19
Journal	International journal of online and biomedical engineering
Volume	22
Issue number	1
DOIs	https://doi.org/10.3991/ijoe.v22i01.58189
State	Published - 22 Jan 2026
Externally published	Yes

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10.3991/ijoe.v22i01.58189

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Iparraguirre-Villanueva, O., Herrera Salazar, J. L., Castro-Leon, G., Ochoa-Carbajal, H., Chero-Valdivieso, H., & Flores-Castañeda, R. O. (2026). Symmetry-Aware Machine Learning for the Diagnosis of Alzheimer’s Disease and Detection of Mild Cognitive Impairment Using Biomarkers. International journal of online and biomedical engineering, 22(1), 21-39. https://doi.org/10.3991/ijoe.v22i01.58189

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title = "Symmetry-Aware Machine Learning for the Diagnosis of Alzheimer{\textquoteright}s Disease and Detection of Mild Cognitive Impairment Using Biomarkers",

keywords = "Alzheimer{\textquoteright}s disease (AD), cognitive degeneration, diagnosis, machine learning (ML)",

author = "Orlando Iparraguirre-Villanueva and \{Herrera Salazar\}, \{Jos{\'e} Luis\} and Gloria Castro-Leon and Hern{\'a}n Ochoa-Carbajal and Henry Chero-Valdivieso and Flores-Casta{\~n}eda, \{Rosalynn Ornella\}",

note = "Publisher Copyright: {\textcopyright} 2026 by the authors of this article.",

year = "2026",

month = jan,

day = "22",

doi = "10.3991/ijoe.v22i01.58189",

language = "English",

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Iparraguirre-Villanueva, O, Herrera Salazar, JL, Castro-Leon, G, Ochoa-Carbajal, H, Chero-Valdivieso, H & Flores-Castañeda, RO 2026, 'Symmetry-Aware Machine Learning for the Diagnosis of Alzheimer’s Disease and Detection of Mild Cognitive Impairment Using Biomarkers', International journal of online and biomedical engineering, vol. 22, no. 1, pp. 21-39. https://doi.org/10.3991/ijoe.v22i01.58189

Symmetry-Aware Machine Learning for the Diagnosis of Alzheimer’s Disease and Detection of Mild Cognitive Impairment Using Biomarkers. / Iparraguirre-Villanueva, Orlando; Herrera Salazar, José Luis; Castro-Leon, Gloria et al.
In: International journal of online and biomedical engineering, Vol. 22, No. 1, 22.01.2026, p. 21-39.

Research output: Contribution to journal › Article › peer-review

TY - JOUR

T1 - Symmetry-Aware Machine Learning for the Diagnosis of Alzheimer’s Disease and Detection of Mild Cognitive Impairment Using Biomarkers

AU - Iparraguirre-Villanueva, Orlando

AU - Herrera Salazar, José Luis

AU - Castro-Leon, Gloria

AU - Ochoa-Carbajal, Hernán

AU - Chero-Valdivieso, Henry

AU - Flores-Castañeda, Rosalynn Ornella

PY - 2026/1/22

Y1 - 2026/1/22

KW - Alzheimer’s disease (AD)

KW - cognitive degeneration

KW - diagnosis

KW - machine learning (ML)

UR - https://www.scopus.com/pages/publications/105029120040

U2 - 10.3991/ijoe.v22i01.58189

DO - 10.3991/ijoe.v22i01.58189

M3 - Article

AN - SCOPUS:105029120040

SN - 2626-8493

VL - 22

SP - 21

EP - 39

JO - International journal of online and biomedical engineering

JF - International journal of online and biomedical engineering

IS - 1

ER -

Iparraguirre-Villanueva O, Herrera Salazar JL, Castro-Leon G, Ochoa-Carbajal H, Chero-Valdivieso H, Flores-Castañeda RO. Symmetry-Aware Machine Learning for the Diagnosis of Alzheimer’s Disease and Detection of Mild Cognitive Impairment Using Biomarkers. International journal of online and biomedical engineering. 2026 Jan 22;22(1):21-39. doi: 10.3991/ijoe.v22i01.58189

Symmetry-Aware Machine Learning for the Diagnosis of Alzheimer’s Disease and Detection of Mild Cognitive Impairment Using Biomarkers

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